You do not have to sacrifice a whole female to make seeds. Pick a lower branch, bag the rest of the plant or move it to a still room, and apply pollen with a small brush to the pistils on that branch alone, then rinse the surrounding area afterward. The step by step method laid out on https://breederregularseeds.com includes a trick of tagging the branch with tape so you remember which buds contain seed at harvest. The rest stays seedless if you are careful with the fans.